Ассоциации
Флаги
Mobile
eye5
askin_heid
Конгресс 2014
Первая пятница декабря
Основные мероприятия ассоциации офтальмологов
Торика
YouTube
santen
medlab
конгресс 2018
cophyaa
glaucoma_net_ru
cophyeu
Шахматы
bannerparasol
oftalmolog_club
facebook
camopht
АйНьюс.РФ
ВК
Beaver
www.worldglaucoma.org
varthamana2
icgs2018
appstore
icglaucoma.org
nidek
Конгресс
профессор
Главная / Новости / Macular Vessel Density in Glaucomatous Eyes with Focal Lamina Cribrosa Defects
9 месяцев назад
18 февраля 2018

Macular Vessel Density in Glaucomatous Eyes with Focal Lamina Cribrosa Defects

Purpose: To compare optical coherence tomography angiography (OCTA) measured macular vessel density and spectral domain optical coherence tomography (SDOCT) measured macular ganglion cell complex (GCC) thickness in primary open-angle glaucoma (POAG) eyes with and without focal lamina cribrosa (LC) defects.

Methods: In this cross-sectional, case-control study of patients with POAG, 46 eyes of 46 patients with LC defects and 54 eyes of 54 patients without observable LC defects were included. OCTA and SDOCT imaging were performed on the same day by the same operator. Perimetry and swept-source OCT testing used to identify LC defects were conducted within 6-months of OCTA and SDOCT testing. Global and local parafoveal vessel density (pfVD) and macular ganglion cell complex (mGCC) thickness were compared between study groups.

Results: Glaucoma severity was similar between groups (SAP MD =−5.63▒dB and −4.64▒dB for eyes with and without LC defects, respectively; P = 0.40). Global and local measured pfVD was similar between groups (all P≥0.11). GCC focal loss volume (GCC-FLV) was higher in eyes with LC defects than eyes without LC defects (7.2% and 4.97%, respectively; P = 0.03). In addition, GCC-FVL was topographically related to defect location in LC defect eyes.

Conclusions: Although OCTA macular vessel density was not significantly different between eyes with and without LC defects, focal GCC loss in eyes with LC defects was different. This highlights the importance of not relying solely on vessel density measurements for determining macular changes for diagnosing and detecting glaucomatous progression.

Голосование
Что "заставляет" Вас заниматься научными исследованиями?